Alcohol Deaths Take Lives of Working-Age Americans

I'm surprised at the research findings.

"Alcohol consumption is a leading preventable cause of death in the US, and death rates from fully alcohol-attributable causes (eg, alcoholic liver disease) have increased in the past decade, including among adults aged 20 to 64 years."

"The findings of this cross-sectional study suggest that an estimated 1 in 8 total deaths among US adults aged 20 to 64 years were attributable to excessive alcohol use, including 1 in 5 deaths among adults aged 20 to 49 years. The number of premature deaths could be reduced with increased implementation of evidenced-based, population-level alcohol policies, such as increasing alcohol taxes or regulating alcohol outlet density."

Source:
Estimated Deaths Attributable to Excessive Alcohol Use Among US Adults Aged 20 to 64 Years, 2015 to 2019 - JAMA Netw Open. 2022;5(11):e2239485. doi:10.1001/jamanetworkopen.2022.39485

CRISPR kills HIV and eats Zika 'like Pac-man'. Its next target? Cancer | WIRED UK

Read the full article:  CRISPR kills HIV and eats Zika 'like Pac-man'. Its next target? Cancer | WIRED UK:

"These new enzymes are variants of a CRISPR protein, Cas13a, which the UC Berkeley researchers reported last September in Nature, and could be used to detect specific sequences of RNA, such as from a virus. The team showed that once CRISPR-Cas13a binds to its target RNA, it begins to indiscriminately cut up all RNA making it "glow" to allow signal detection."

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Obesity More Deadly for Men Than Women: Study - philly.com

Read the full article: Obesity More Deadly for Men Than Women: Study - philly.com:

"In a study of nearly 4 million men and women around the globe, the risk of dying before the age of 70 was 19 percent for men and 11 percent for women of normal weight.

But that risk jumped to 30 percent and 15 percent, respectively, for obese men and women. That's an absolute increased risk of 11 percent for men and 4 percent for women, the researchers reported."

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Is the mythical "five-second rule" actually real? - CBS News

Is the mythical "five-second rule" actually real? - CBS News:

"New research finds that there is some truth to the so-called "five-second rule" -- the belief that food is safe to eat if picked up from the floor in under five seconds.

Researchers at Aston University in Birmingham, U.K. studied the rate of bacteria transfer in food items dropped on the floor and picked up within three to 30 seconds. They found that the amount of time an item spent on the floor was directly related to bacteria levels."

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Healthcare organizations under siege from cyberattacks, study says - latimes.com

Healthcare organizations under siege from cyberattacks, study says - latimes.com:

"The study was conducted by Norse, a Silicon Valley cybersecurity firm, and SANS, a security research institute. In the report, the groups found from September 2012 to October 2013 that 375 healthcare organizations in the U.S. had been compromised, and in many cases are still compromised because they have not yet detected the attacks.  In addition to getting access to patient files and information, the attackers managed to infiltrate devices such as radiology imaging software, conferencing systems, printers, firewalls, Web cameras and mail servers."

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mHealth to see big growth, barriers | Healthcare IT News

mHealth to see big growth, barriers | Healthcare IT News:

"A new mobile health trends report released Wednesday underscores the mid- to low sophistication of current mHealth application technology but also emphasizes the explosive growth and integration headed for the market .

The Research and Markets mHealth trends report shows the industry poised for a compound annual growth rate of 61 percent by 2017, to reach a value of $26 billion. This revenue, researchers project, will be derived predominantly from mHealth hardware sales and services."

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Hand Washing - Only 5% Do It Well Enough

The art of hand washing has yet to be mastered:

"According to a study led by Borchgrevink, only 5% of people washed their hands enough to kill infection and illness causing germs after using the bathroom. To make matters worse, 33% of hand washers didn't use soap, and 10% skipped the hygienic step altogether.

"It's horrifying," Borchgrevink says. "A majority didn't even make an effort.""

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Olive Oil Aroma Might Make You Feel Full

Olive oil the key to feeling full? | ScienceBlog.com:

“Our findings show that aroma is capable of regulating satiety,” concludes Schieberle. “We hope that this work will pave the way for the development of more effective reduced-fat food products that are nonetheless satiating.”

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FDA Awards Two New Regulatory Research Centers

Image via WikipediaFDA launches two centers to improve approval of drugs, devices - The Hill's Healthwatch:  'via Blog this'

"The Food and Drug Administration (FDA) on Wednesday awarded $2 million to support the creation of research centers tasked with improving the way new medicines and medical devices are reviewed and evaluated."

The centers will be established at the University of Maryland and Georgetown University.

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FDA Awards University Consortium To Improve Drug Manufacturing

Drug shortages: University of Maryland, other universities work to improve drug manufacturing process - baltimoresun.com:   'via Blog this'

The Food and Drug Administration (FDA) has given "a $35 million grant to" the National Institute for Pharmaceutical Technology and Education, a group of 11 universities, "to make the nation's drugs safer and less costly, and even produce more jobs, by improving the science of manufacturing."

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Colon Cleansing Risky - Controversy

Updated Sept 8, 2016

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You Asked: Is Getting a Colonic Dangerous? - TIME

- -  original post follows below  - -

I've never had a colon cleanse, though I know friends who swear by them.

I'm inclined to avoid them, after reading about the latest findings reported by Mishori (reported in the Journal of Family Practice).

For a quick read, go to WebMD and read, Colon Cleansing May Be Risky, Study Finds - Hazards May Include Nausea, Vomiting, Kidney Failure; Advocates Cite Energy Boost, Other Health Benefits.

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FDA Finds Faked Documentation At Cetero

This is a really good example of how improper documentation practices can get a company into real trouble.

Read this Reuter's release, FDA finds drug research firm faked samples, documents.

In a nutshell:

"The pattern of misconduct was serious enough to raise concerns about the integrity of the data Cetero generated during the five-year time frame," the FDA said, warning drugmakers they might have to repeat or confirm any studies Cetero did in support of their applications between April 2005 and June 2010.

Clinical Study Of Disulfiram To Reduce HIV Reservoir

Image via WikipediaThis caught my eye while scanning health news, Short-term Disulfiram Administration to Accelerate the Decay of the HIV Reservoir in Antiretroviral-treated HIV Infected Individuals.

This ClinicalTrials.gov notice provides robust details about the research study, which is actively recruiting participants.

I find the basis for the study pretty interesting:

"Our primary hypothesis is that disulfiram will reduce the latent reservoir of HIV-1 in patients on highly active antiretroviral therapy (HAART). Theoretically, disulfiram will force HIV to replicate (grow) and thus result in the death of the infected cell. Standard antiretroviral drugs should prevent new cells from becoming infected. The end result of this process is that the total amount of HIV in the body will decline over time."

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Future Pills - Drugs, Devices, and More

An interesting intersection of drugs and medical devices, reported in this LA Times article, Smarter Pills - BEEP! BEEP! BEEP! This is your medicine. It's time for another dose.

In a nutshell,

"The goal: new devices to help people take their meds on time and improve the results coming out of clinical trials for new drugs."

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More Aspirin Benefit - Cancer Prevention - I Love It

I started taking a daily dose of aspirin well over a decade ago, in hopes that the anecdotes of cancer prevention benefit would one day morph into evidence-based data. Voila!



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Univ of CA CMCR - Evidence Cannabis Is A Promising Treatment

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The Center for Medicinal Cannabis Research: Report to the California Legislature (2010) - pdf reports:

"The CMCR has successfully conducted the first clinical trials of smoked cannabis in the United States in more than 20 years. As a result of this program of systematic research, we now have reasonable evidence that cannabis is a promising treatment in selected pain syndromes caused by injury or diseases of the nervous system, and possibly for painful muscle spasticity due to multiple sclerosis."

Learn More:
Understanding Marijuana: A New Look at the Scientific Evidence

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HIV AIDS - 97 US Medicines in Testing - PharmaTimes

Image via Wikipedia

Updated November 26, 2025

The original link broke.

You can still read about the same topic here:

U.S. Pharmaceutical Companies Developing 97 New Drugs and Vaccines to Fight HIV/AIDS - MedIndia:
https://www.medindia.net/health-press-release/US-Pharmaceutical-Companies-Developing-97-New-Drugs-and-Vaccines-to-Fight-HIVAIDS-53732-1.htm

---  the original post follows below  ---

This is a really nice snapshot of some of the clinical testing going on in the HIV AIDS field, PhRMA's Pharmaceutical Researchers Are Testing 97 Medicines And Vaccines for HIV and Related Conditions. The article provides a quick overview for medicines grouped by:

1. Anticancer
2. Antiviral
3. Gene therapy
4. Immunomodulators
5. Vaccines
6. Other

Previous Posts: Abzymes Pinpoint The HIV Achilles Heel 109 HIV Drugs And Vaccines Under Development Listen To People With AIDS and HIV (audio)

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Recent HIV Vaccine Study Results - Could be disappointing

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Updated January 14, 2024

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HIV vaccine research ‘at a crossroads’ after recent failures - Healio

---  the original post follows below  ---

Optimism generated from a recent HIV vaccine study conducted by the US Army & Thailand, might not be justified after all, reports this Wall Street Journal article, Data Call Into Question HIV Study Results. The statistical analysis is discussed, and calls into question the conclusions reached and recently publicized. I think there's more to come on this. 

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LSD Research Returns - FDA and Regulatory Oversight

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What a surprise to read this fascinating San Francisco Chronical article, LSD's long, strange trip back into the lab. According to the article:

It still isn't easy to get an LSD study off the ground. Researchers must get permission from the U.S. Food and Drug Administration and the Drug Enforcement Administration plus state regulators, and they need approval from the institution they work for. Then they have to get approval for the source of the actual drug - in the case of UCSF, researchers are using LSD that was manufactured years ago in Switzerland.

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FDA To Share Nanotoxicology Information

According to this FDA Law Blog post, Nanotech Update: FDA Enters Into MOU With Air Force Research Laboratory to Facilitate Sharing of Nanotoxicology Information, "FDA’s National Center for Toxicological Research (“NCTR”) has entered into a Memorandum of Understanding (“MOU”) that provides for the sharing of nanotoxicology information with the Air Force Research Laboratory, 711 Human Performance Wing, Human Effectiveness Directorate, Biosciences and Protection Division (“AFRL”). " 

Previous Posts: Hidden Health and Financial Liabilities of Nanotechnology Should The FDA Oversee Nanotechnology Dietary Supplements? 

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