FDA Says Giving Bones To Dogs Is Unsafe

The FDA says don't give your dog a bone.  Here are 10 reasons why it’s a bad idea to give your dog a bone:

1. Broken teeth.
2. Mouth or tongue injuries.
3. Bone gets looped around your dog’s lower jaw.
4. Bone gets stuck in esophagus, the tube that food travels through to reach the stomach.
5. Bone gets stuck in windpipe.
6. Bone gets stuck in stomach.
7. Bone gets stuck in intestines and causes a blockage.
8. Constipation due to bone fragments.
9. Severe bleeding from the rectum.
10. Peritonitis.

Basically, all of these end up with a visit to a vet due to serious injury or death. For more details and explanations, read on:

FDA - No Bones About It: Bones are Unsafe for Your Dog


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HIV AIDS - Gene Research Shows Promise

Jay Levy of UCSF wrote a recent editorial in the NEJM (Levy, NEJM, 2/12/09), as reported in this Medical News Today article, New HIV/AIDS Research Directions Show Promise, NEJM Editorial Says. This is the first time I've read about this, and find it incredibly fascinating and exciting. Here are my takeaways from reading the article . . .

1. Recent HIV/AIDS research that examines the role certain genes play in inhibiting HIV progression shows promise for the development of new treatment measures
2. HIV enters the body through CD4+ T cells and then binds to the chemokine receptors CCR5 and CXCR4.
3. Research has found that people whose cells lack expression of the CCR5 gene typically demonstrate resistance to the virus.
4. Researchers examined the case of an HIV-positive patient with myelogenous leukemia who received a bone marrow transplant from a person whose cells lacked expression of the CCR5 gene. After two transplants, the researchers determined that the patient had no leukemia recurrence and no detectable level of HIV in the bloodstream
5. Levy says, "the result of this study [reported in the same NEJM issue] and others provide further encouragement for those examining approaches to treatment that reduce CCR5 [receptor] expression in persons with HIV." This is the study Levy refers to, Brief Report: Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation (summary).

Related Posts: 

CDC Adopts 2 New HIV Intervention Approaches
HIV Pre Exposure Prophylaxis - Very Sharp Two Edged Sword
Abzymes Pinpoint The HIV Achilles Heel
109 HIV Drugs And Vaccines Under Development
HIV AIDS Bone Marrow Transplant Cure - Skeptical View
HIV Treatment Goes Bionic
HHS Updates HIV Treatment Guidelines (free pdf)

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HIV AIDS Bone Marrow Transplant Cure - Skeptical View

Updated February 17, 2021

More current news:

Maryland HIV researcher on latest research: It's not a cure - WBAL-TV:

"Scientists used a cutting-edge stem cell transplant method to treat a woman's HIV, but a lead researcher in Maryland said it's too soon to celebrate. A U.S. woman is the third known person who is in HIV remission after receiving stem cells from umbilical cord blood, an American research team announced Wednesday."

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Updated May 1, 2021

The original link broke.

You can read more about the topic at:

Is “Cure” Still A Four-Letter Word? (PDF) - sfaf.org

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Don't get me wrong, I'm excited about this latest case report. However, there are alternate views of what this really means. See what I mean by reading this ABC Health Insider news article, "For AIDS, 'Cure' Is Still a Four-Letter Word." There are a couple of ways to think about this. If bone marrow transplantation really works in the long run, how do we make it widely available and affordable?! If it doesn't work, how long will it take to definitively confirm its ultimate failure?! What's your opinion? 

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